Epidemiological research on radiation-induced cancer in atomic bomb survivors
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Epidemiological research on radiation-induced cancer in atomic bomb survivors
The late effects of exposure to atomic bomb radiation on cancer occurrence have been evaluated by epidemiological studies on three cohorts: a cohort of atomic bomb survivors (Life Span Study; LSS), survivors exposed IN UTERO : , and children of atomic bomb survivors (F1). The risk of leukemia among the survivors increased remarkably in the early period after the bombings, especially among child...
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Radiation has been associated with increases in noncancerous diseases. An effect of low-dose radiation on the prevalence of clinically detected glaucoma has not been previously reported. We therefore investigated the prevalence of glaucoma in A-bomb survivors and its possible association with radiation dose. A total of 1,589 people who participated in the clinical examination program for A-bomb...
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EUKEMOGENESIS induced by repeated exposures to x-ray and other forms of radiation energy has long been recognized in man and in experimental ammals.’3 The explosion of the atomic bombs in Japan exposed two large human populations to single brief but massive doses of ionizing irradiation and subsequently a marked increase in leukemia among survivors was reported.4 ‘ The present study consists of...
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Results are given on the joint effect of radiation exposure and cigarette smoking on lung cancer risks among A-bomb survivors, based on 592 cases through 1994. Information on smoking was derived from mail surveys and clinical interviews of 45113 persons in the Radiation Effects Research Foundation cohort. Radiation and smoking effects on lung cancer are found to be significantly sub-multiplicat...
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While radiation increases the risk of lung cancer among members of the Life Span Study (LSS) cohort of atomic bomb survivors, there are still important questions about the nature of its interaction with smoking, the predominant cause of lung cancer. Among 105,404 LSS subjects, 1,803 primary lung cancer incident cases were identified for the period 1958-1999. Individual smoking history informati...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2016
ISSN: 0449-3060,1349-9157
DOI: 10.1093/jrr/rrw005